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The functional characterization of proteins is especially challenging because proteins have flexible structures, transiently existing in a continuum of structural and functional states. SeraFILE™ - ProFACT Proteomics' surface library and associated separations protocols, uniquely differentiates and compartmentalizes the functional characteristics of proteomes. From these sub-proteomes, derivative molecular profiles can make connections to functional mechanisms, small molecule modulation and gene expression.
Clients and collaborators now employ SeraFILE™ to simultaneously survey the functional characteristics of a targeted protein set for: feature comparisons and discovery of biomarkers and drug targets, for low-abundance enrichment, and for new proteomic prospecting strategies.
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Your research will benefit if you:
Introduction to Molecular Profiling Services
ProFACT’s Molecular Profiling Services include: SeraFILE™, for reduction of protein complexity and sub-proteome creation; Rational Proteome Prospecting™, to enrich and isolate functional activity; Conformerics™, to generate drug screening assays based on enzyme sub-states or conformers; and Rational Genome to Proteome Prospecting™, for prospecting into protein expression based on gene expression data.
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